Department of Bioengineering
Digital Bat Twins – NeuroAI generates testable hypotheses about higher-level cognitive function
Researchers in Michael Yartsev's lab, led by postdocs Adam Lowet and Krishna Kasuba, built a digital twin of the bat hippocampus - an AI model trained on large-scale neural activity during natural flight. The model generated new, testable hypotheses about hippocampal organization that were confirmed by real-world data.
Categories: Science News
NATIVE-ID Seeks to Prevent Neurodegenerative Diseases by Learning the Language of Disordered Proteins
ARPA-H's BIOGAMI program aims to transform our understanding of protein dysfunction in the earliest stages of neurodegenerative disease by developing new approaches to detect and characterize protein misfolding. BioE PhD alumnus Nicolas Fawzi leads the Brown University team on this multicampus, led at Berkeley by the Innovative Genomics Institute.
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From bat flight to the most complex human movements
Examining large-scale neural activity from the motor cortex of freely flying Egyptian fruit bats helps Michael Yartsev's lab understand how the brain supports very complex behaviors, like buttoning a shirt or playing piano.
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Solving a longstanding problem in drug delivery
Lipid nanoparticles are great delivery vehicles for mRNA treatments, but their positive charge triggers high levels of inflammation. Now researchers led by Professor Niren Murthy have engineered a new lipid nanoparticle that can switch its charge from positive to negative and may avoid triggering inflammation while still able to deliver mRNA and other nucleic acids.
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In Memoriam: Prof. David Rempel
It is with great sadness that we recognize the passing of Dr. David Rempel, MD, MPH, CPE. A versatile expert in occupational health and long-time member of the Bioengineering Graduate Program, he was a Professor Emeritus of Medicine at UCSF and Bioengineering Berkeley. He will be missed.
Categories: Science News
How One Simple Change Can Make Lipid Nanoparticles Safer for Gene Editing and Other Applications
In a new paper out in Nature Nanotechnology, researchers in Niren Murthy’s lab show that there is a simple way to remove the toxicity of lipid nanoparticles while maintaining their ability to effectively deliver therapies to specific cells in the body.
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2024 Fractal cane design on irregular surfaces
Title: Fractal cane design on irregular surfaces Names: Derrick Ma, Briana Gonzalez, Hamreet Pannu, Mridini Vijay. Client:Dr. Janice Schwartz and Dr. Evie Kalmar, UCSF Geriatrics Division.
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Overton wins SCP Best Poster
Congratulations to PhD student Maya Overton of Herr Lab, winner of Best Poster at the Single Cell Proteomics Conference (SCP2026)!
Categories: Science News